Iron Culture presented by MASS

Ep 387 - Energy Cost of Building Muscle

August 26, 2026·1h 2m
Episode Description from the Publisher

In this episode, Eric Trexler and Eric Helms explore the energetic cost of building human skeletal muscle, discussing recent research, practical implications, and misconceptions about muscle growth and energy expenditure.Relevant papers:https://pubmed.ncbi.nlm.nih.gov/31482093/https://pubmed.ncbi.nlm.nih.gov/37914977/https://www.biorxiv.org/content/10.64898/2026.08.17.745156v1.full.pdfCatch new Iron Culture episodes every Tuesday at 5:30 pm eastern time!Be sure to use code "MRR10" for 10% off your order at elitefts.comIron Culture is proudly presented by the MASS Research Reviewmassresearchreview.comChapters00:00 Introduction01:52 Powerlifting shout-out11:55 Introduction to new paper on energetic cost of building muscle20:01 Components of muscle tissue building and their energy costs22:59 Practical implications of the 3500 calorie rule30:05 The five additive components of muscle growth energy cost33:49 Variability in individual energy expenditure responses40:12 Limitations and future directions in research50:10 Summary and concluding thoughts

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