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Intro to Clinical Research: Daily Summaries Delivered
by Debbie and Elyse
Welcome to the Introduction to Clinical Research Podcast! Join Debbie, a clinical research professional, as she explains clinical research to her friend Elyse. Curious how the COVID vaccine was developed so quickly? Ever wondered what rules determine when you can get a new drug? Remember that one miracle drug they swore would cure cancer back in 2002 but then you never heard of it again? Let’s talk about that.
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- 2 days ago46 min
Episode 61 - Research in the News
It’s time for us to update you on current events, medical research or drugs in the news! We’ve got a few stories at different points in their research journey, from just getting started to failing publicly, and an update on regulation changes in the UK. Remember, you can get in touch with us via clinical.research.intro@gmail.com. Please feel free to send questions, comments and compliments for Elyse to read out on the pod. It’s fun to make Debbie squirm! Credit to our friend Sam Winnie for their awesome and cute music. Check out their work at https://www.samwinnie.com/ References - https://www.bbc.co.uk/news/articles/c4gllr5y3n2o https://www.theguardian.com/science/2026/may/30/cancer-jab-can-eradicate-entire-tumours-in-patients-trial-shows https://www.theguardian.com/science/2026/may/30/trial-of-multi-cancer-blood-test-among-142000-nhs-patients-fails-to-meet-main-aim https://www.legislation.gov.uk/uksi/2025/538 https://www.hra.nhs.uk/planning-and-improving-research/policies-standards-legislation/clinical-trials-investigational-medicinal-products-ctimps/clinical-trial-regulations-reform/
- 3 weeks ago57 min
Episode 60 - Elyse's Corner: The Interstitium
Episode 60 In this episode, we’re back in Elyse’s corner (hooray!), and today, we’re talking about the interstitium (with a prelude into the human lymphatic system). Don’t worry if you have no clue what either of those things are, we’re doing a basic guide today but check out the references for much more info! Remember, you can get in touch with us via clinical.research.intro@gmail.com. Please feel free to send questions, comments and compliments for Elyse to read out on the pod. It’s fun to make Debbie squirm! Credit to our friend Sam Winnie for their awesome and cute music. Check out their work at https://www.samwinnie.com/ References - https://www.nature.com/articles/s41598-018-23062-6.pdf https://pmc.ncbi.nlm.nih.gov/articles/PMC6399417/ https://www.scientificamerican.com/article/meet-your-interstitium-a-newfound-organ/ https://www.nytimes.com/interactive/2026/05/11/magazine/interstitium-anatomy-acupuncture-medicine.html
- Jun 15, 202649 min
Episode 59 - Interpretation of ICH GCP part 2
This is part 2 of our discussion on interpretation of GCP. If you haven’t listened to part 1, I recommend going and checking that out first. We’re covering a few more examples where ICH GCP sets out the principles and practices that should be followed to have harmonised, quality research. Remember, you can get in touch with us via clinical.research.intro@gmail.com. Please feel free to send questions, comments and compliments for Elyse to read out on the pod. It’s fun to make Debbie squirm! Credit to our friend Sam Winnie for their awesome and cute music. Check out their work at https://www.samwinnie.com/
- May 25, 202651 min
Episode 58 - Interpretation of ICH GCP part 1
Today, we’re finally getting into why Debbie says “it depends” so much in answer to many of Elyse’s questions. We’re looking at how ICH GCP sets out the principles and practices that should be followed to have harmonised, quality research. This is part 1, so stay tuned for part 2 following soon! Remember, you can get in touch with us via clinical.research.intro@gmail.com. Please feel free to send questions, comments and compliments for Elyse to read out on the pod. It’s fun to make Debbie squirm! Credit to our friend Sam Winnie for their awesome and cute music. Check out their work at https://www.samwinnie.com/
- May 4, 202650 min
Episode 57 - Medical Ethics
Today, Debbie throws us all back into the Philosophy Ravine together to discuss medical ethics. We’re going to talk about what it is and use the framework of Medical Ethics to consider two case studies - the Minnesota Starvation Experiments and Covid-19 Challenge Studies. Content Warning - this podcast does discuss WW2, and experiments where patients chose to restrict their access to food. Remember, you can get in touch with us via clinical.research.intro@gmail.com. Please feel free to send questions, comments and compliments for Elyse to read out on the pod. It’s fun to make Debbie squirm! Credit to our friend Sam Winnie for their awesome and cute music. Check out their work at https://www.samwinnie.com/ References - https://www.bmj.com/content/371/bmj.m4258#:~:text=In%20the%20current%20pandemic%2C%20over%2038%20000,a%20non%2Dprofit%20organisation%20advocating%20for%20these%20volunteers https://www.bbc.co.uk/news/health-56097088#:~:text=Getty%20Images,more%20than%2015%20million%20people. https://www.pushkin.fm/podcasts/revisionist-history/the-rise-of-the-guinea-pigs https://thispodcastwillkillyou.com/2025/10/14/episode-190-starvation-more-than-hunger/ Firsthand: The Minnesota semi-starvation experiment, University Publications, Archives & Special Collections, Colorado State University https://hdl.handle.net/10217/02.0036381
- Apr 13, 202651 min
Episode 56 - International Collaboration
In this episode, we’re going to be discussing some international collaborations in clinical research! Let’s cross some borders and work together! Remember, you can get in touch with us via clinical.research.intro@gmail.com. Please feel free to send questions, comments and compliments for Elyse to read out on the pod. It’s fun to make Debbie squirm! Credit to our friend Sam Winnie for their awesome and cute music. Check out their work at https://www.samwinnie.com/ References - https://www.ema.europa.eu/en/partners-networks/international-activities/multilateral-coalitions-initiatives/opening-procedures-ema-non-eu-authorities-open-framework Who Guidance for Best Practice on Clinical Trials - https://iris.who.int/server/api/core/bitstreams/dbe6d97c-b659-4e7b-8070-b4a3c667d6e5/content https://picscheme.org/en/about
- Mar 30, 202654 min
Episode 55 - Safety Events & Investigator's Brochure
Hey everyone! We’re back (again!) and we hope you didn’t miss us too much. In this episode, we’re going to be discussing safety events, safety reporting and the compilation of information in the Investigator’s Brochure. Remember, you can get in touch with us via clinical.research.intro@gmail.com. Please feel free to send questions, comments and compliments for Elyse to read out on the pod. It’s fun to make Debbie squirm! Credit to our friend Sam Winnie for their awesome and cute music. Check out their work at https://www.samwinnie.com/
- Dec 22, 202548 min
Episode 54 - Medical Devices
Hey everyone! We’re back and we hope you didn’t miss us too much. In this episode, we’re diving right back in and talking about Medical Devices - what they are, how varied they can be, and how they’re regulated (in general terms!) Remember, you can get in touch with us via clinical.research.intro@gmail.com. Please feel free to send questions, comments and compliments for Elyse to read out on the pod. It’s fun to make Debbie squirm! Credit to our friend Sam Winnie for their awesome and cute music. Check out their work at https://www.samwinnie.com/ References https://www.ema.europa.eu/en/human-regulatory-overview/medical-devices https://www.fda.gov/medical-devices/regulatory-controls/general-controls-medical-devices https://www.fda.gov/medical-devices/guidance-documents-medical-devices-and-radiation-emitting-products/class-ii-special-controls-documents https://www.fda.gov/media/82395/download https://www.gov.uk/guidance/medical-devices-how-to-comply-with-the-legal-requirements https://hollandhoudek.com/implants
About Intro to Clinical Research
Welcome to the Introduction to Clinical Research Podcast! Join Debbie, a clinical research professional, as she explains clinical research to her friend Elyse. Curious how the COVID vaccine was developed so quickly? Ever wondered what rules determine when you can get a new drug? Remember that one miracle drug they swore would cure cancer back in 2002 but then you never heard of it again? Let’s talk about that.
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