Intelligent Medicine with Dr. Ronald Hoffman | The Best of High Tech Medicine and Alternative Modalities

Microbiome Basics: How Pre-, Pro-, and Postbiotics Support Health, Part 1

September 15, 2026·24 min
Episode Description from the Publisher

Dr. Ross Pelton, Director of Science & Education for Essential Formulas Incorporated, maker of Dr. Ohhira’s premium probiotic products, reveals how the gut microbiome affects metabolism, appetite, weight regulation, and overall health. He emphasizes the importance of microbiome diversity, supported by eating a wide variety of plant foods rich in fiber and polyphenols, and discusses how fermented foods and postbiotic metabolites help maintain a healthy gut environment. Pelton explains Dr. Ohhira’s multi-year fermentation process and the idea that postbiotics may be key health regulators. He reviews studies suggesting benefits from Dr. Ohhira’s probiotics for athletic performance markers, reduced fatigue, and improved bowel regularity, and notes research showing antibiotic-related losses in gut diversity can persist for years. He also mentions a higher-dose “Reset Challenge,” a postbiotic paste concentrate, and an ME-3 product aimed at increasing glutathione.

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