Healio Rheuminations

Healio Community Book Club: A conversation between Leonard Calabrese, DO and Kevin Tracey, MD, author of The Great Nerve

February 24, 2026·40 min
Episode Description from the Publisher

This special edition episode features the latest installment of Healio Community's book club. Physician author Kevin J. Tracey, MD, discussed his book, The Great Nerve: The New Science of the Vagus Nerve and How to Harness Its Healing Reflexes in which he explores the potential of stimulating the vagus nerve to treat rheumatoid arthritis and other diseases. ·        Intro by Adam J. Brown, MD 0:14 ·        A warm welcome from Leonard H. Calabrese, DO 0:25 ·        Introducing Kevin J. Tracey, MD 0:58 ·        The connection between the brain and the immune system 3:25 ·        Where was the switch that combined neural networks and immune response? 5:55 ·        A brief summary of the main parts of The Great Nerve: The New Science of the Vagus Nerve and How to Harness Its Healing Reflexes 9:18 ·        The science of vagal nerve stimulation 11:03 ·        What are the pros and cons of different strategies of stimulating the vagus nerve? 16:28 ·        Different inflammatory responses to implant devices 17:35 ·       </sp

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