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Grow Everything Biotech Podcast: Daily Summaries Delivered
by Messaginglab
Grow Everything explores the world of biology as technology. Hosts Erum Khan and Karl Schmieder interview leaders and influencers biologizing industries with tools like synthetic biology, precision fermentation, bioprospecting, and more. These companies make biomaterials from waste, cosmetics that restore healthy hair and skin, and delicious cultivated foods in a bioreactor and so much more. Join us as we discuss the latest and greatest across biotech, engineered biology, entrepreneurship, and culture and how this transition is solving healthcare and climate change challenges.
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- 1 weeks ago52 min
205. The Sweet Taste of Negative Waste: Max Kufner Ferments Carbon Waste at Again
What does it take to turn industrial carbon dioxide into useful chemicals at a price the market will accept? On Grow Everything, Karl Schmieder and Erum Azeez Khan speak with Max Kufner, cofounder and CEO of Again, about using gas fermentation to make acetate and other products from industrial emissions. Max explains why feedstock economics and locating production close to customers matter, what the acquisition of Genomatica brings to Again, and why real production data is essential for predicting whether a bioprocess can work at industrial scale. He also shares how customer demand, licensing, project finance, and partnerships can help move biotechnology from the lab into the real world. Before the interview, the hosts explore an AI assisted biomanufacturing class and the latest discussion around deextinction.Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and speak with the leaders and innovators using biology to change the world. Biology is the world’s oldest technology, and it can be engineered. So, what are we growing?Learn more at www.messaginglab.com/groweverythingChapters: - Biology, public engagement, and biomanufacturing education - AI agents and cell free protein experiments - Deextinction, the moa, and biotechnology - Max Kufner on turning carbon dioxide into chemicals - From venture capital to building Again - Industrial bioreactors and manufacturing at the source - Financing biotechnology scale with customer partnerships - Building biomanufacturing facilities in the US and Europe - Climate tech quick fire: engineers, finance, and teamwork - Founder takeaways: customer demand and cost parityLinks and Resources:Again Bio.Max Kufner LinkedInStartup, Again: Turning CO₂ Emissions into Carbon-negative ChemicalsAgain acquires Geno to combine AI-driven discovery with industrial biomanufacturingColossal, who de-extincted the dire wolf, now hatches chicks from artificial egg to help de-extinct moa113. Microbe Mission Possible: Noah Helman Discusses iMicrobes' Quest to Turn Waste into Wealth170. There's a Bug for That: Sophia Xu on CarbonBridge's Notebook Bioreactors102. Waste into WOW! Cemvita's Moji Karimi on Turning Carbon Problems into Golden OpportunitiesGrow everything LinkedIn Topics Covered:biomanufacturing, AI x bio, climate tech, green chemicals, sustainable manufacturing, industrial biotechnology, biotech scale-up, deep tech financing, carbon-negative products, alternative chemicalsHave a question or comment? Message us here:Text or Call (804) 505-5553Instagram / Twitter / LinkedIn / Youtube / Grow Everything
- 2 weeks ago1h 13m
204. Moore's Law Than Meets the Eye: Michael Wright's Blueprint at Biomimetics International
Michael Wright, founder of Biomimetics International, joins Grow Everything to explain how learning from nature can reshape the way we design products, build businesses, and scale emerging industries. Drawing on decades in semiconductors and high technology, he describes biomimetics as learning from nature’s tested systems, from burr inspired Velcro to shark skin that reduces drag, while emphasizing that copying a biological function is not enough if a product cannot return safely to the biosphere. He introduces the Biosverse, nature’s third number, and generational cost of ownership as ways to account for environmental liabilities that traditional business models may overlook. The conversation explores how digital and biological systems converge, why biotech can learn from semiconductor standards and roadmaps, how AI might benefit from a more nurturing and accountable design approach, and why leaders should ask, “Do you know what you do does?” Michael’s vision is a mindset shift that brings nature into the design process before we build, then measures whether innovations can serve communities and remain compatible with the living world.Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and speak with the leaders and innovators using biology to change the world. Biology is the world’s oldest technology, and it can be engineered. So, what are we growing?Learn more at www.messaginglab.com/groweverythingChapters: Grow Everything opening and biotech headlines, from fall foliage to food systems for Mars FDA inspections, peptide manufacturing, and the importance of knowing where products come from Michael Wright’s semiconductor career and the path to biomimetics How digital and biological systems converge, from precision agriculture to digital water The Biosverse, biosphere compatibility, and nature’s third number Generational impact, executive decisions, and long term costs What biotech can learn from semiconductor roadmaps, standards, and shared infrastructure AI as a mom, biological sensing, and symbiotic decision making Michael’s dream project: a mindset shift toward looking at nature first Quick fire questions, the episode debrief, and designing data centers with nature in mindEpisode Links: Biomimetics InternationalMichael WrightThe Exponential Era by David Espindola and Michael WrightNASA Mars to Table ChallengeFall foliage tracker in NYBlack mold, bugs found at Chinese plants making GLP-1 compounding agentsCemvita and Roebling Partner to Accelerate Industrial BioSolutions From Discovery to Deployment199. Space, the Final Fermenter: Mario Maggio Brews Biology in Orbit with Ambrosia Space156. When Matter Makes Decisions: Michael Levin on the Intelligence of Form133. Funding, Frameworks & Frenemies: Dr. Angela Belcher of NSCEB Gets Real on the $15B Biotech Boost Plan<a href="https://open.spotify.com/episode/58Rapn3xGI3qGqeszKI9KH?si=gqhBz0wWQfKCWzraJEl9-g" target="_blank" rel="noopener noreferre
- 3 weeks ago48 min
203. The Valley of Do: Karl & Erum Orchestrate Bio-Ecosystems at Bioinnovations Conference
At Bio Innovations in Omaha and an adjacent investor gathering in Houston, Grow Everything hosts Karl Schmieder and Erum Azeez Khan unpack the shift reshaping the bioeconomy: scientific discovery is becoming faster and less expensive, while deployment, scale up, and durable partnerships have become the real competitive advantage. They share conversations from the conference floor on the missing middle between bench science and commercial production, the Midwest’s feedstock and infrastructure advantage, the need for early technoeconomic discipline, and how corporates can give innovators clearer demand and specification targets. From pilot facilities and downstream processing to waste to value opportunities and resilient domestic supply chains, this recap maps the practical work required to turn biological innovation into products that matter.Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and speak with the leaders and innovators using biology to change the world. Biology is the world’s oldest technology, and it can be engineered. So, what are we growing?Learn more at www.messaginglab.com/groweverythingChapters: Halloween, food dyes, and a motel room microbiology discovery The fire microbe and the promise of extremophiles for manufacturing AI agents, scientific discovery, and physical laboratories Bio Innovations recap: Omaha infrastructure meets Houston capital Discovery is cheaper, but deployment is the whole game The missing middle: pilots, ecosystems, and the valley of do Business models, corporate demand clarity, and consumer framing Scale up lessons: feasibility, downstream processing, and tech transfer Waste to value, bioeconomic resilience, and what comes nextLinks and Resources:BioinnovationsSteve Bray - TritenIAGPhillip Crawford -RoeblingMike Glasspool - MerrickKyle Pomraning - Pacific Northwest National LabGatorade recall across 37 states in the U.S.Scientist discovered two new species of bacteria from a motel room they converted into a labIncendiamoeba cascadensis. This 'fire amoeba' pushes the limit of what's possible for complex lifeClaude discovers a novel enzyme system with CRISPR-like repeatsC5R Built a Research Lab Run by AI in 12 Weeks.164. From Plasmids to Pallets: How Erin Marasco Scales Biology at Cargill165. Biology Behind the Brands: Inside P&G’s Two-Century Story166. The Great Reformulation: Joshua Lachter Rethinks How We Make Everything at Scale102. Waste into WOW! Cemvita's Moji Karimi on Turning Car
- 4 weeks ago53 min
202. Setting Sail for Biotech Scale: Jenny Rooke Steers Innovators at Genoa Venture
Genoa Ventures founder and managing director Jenny Rooke joins Karl Schmieder and Erum Azeez to explore bioconvergence, the expanding frontier where biology meets AI, automation, materials science, and real world business building. Drawing on her journey from physics and genetics to venture capital, Jenny explains why durable bio based companies must pair novel science with clear customer demand, disciplined scale up, and a path to meaningful commercial value. The conversation examines lessons from early synthetic biology, the realities of biomanufacturing at scale, next generation clinical assessment tools, and why founders working between traditional tech and biotech categories need investors who understand both.Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and speak with the leaders and innovators using biology to change the world. Biology is the world’s oldest technology, and it can be engineered. So, what are we growing?Learn more at www.messaginglab.com/groweverythingChapters: Climate Week, bioliteracy, and biology as a climate solution America’s Living Library Act and the case for sampling public lands State microbes, public engagement, and the future of bioliteracy Erum’s biomanufacturing course and designing food safe colors Introducing Jenny Rooke and Genoa Ventures From physics and genetics to investing in science based companies The Genoa sail: founder autonomy, trust, and avoiding fatal mistakes What defines a bioconvergence company Why biotechnology needs a broader frame than pharma Lessons from synthetic biology’s first wave and the impact of AI Matching company timelines to biology, markets, and venture returns The future of clinical assessment tools and actionable health data Diagnostics, consumer data, and the difference between insight and infotainment Why bio based businesses can offer investors a different risk profile Why industrial biotechnology companies fail and what scale up requires Biomanufacturing, commercial readiness, and Genoa’s newest investment What Genoa is watching across tools, biology, and manufacturing Jenny’s four word credo and the founder mindset Closing reflections on bioconvergence and building the bioeconomyLinks and Resources:Genoa VenturesJenny Rooke LinkedInGenoa Ventures LinkedInJPM 2026: Genoa Ventures’ Jenny Rooke on Next-Gen Clinical Assessment ToolsGraveyard report - First Bite Ventures3 States Have Official State Microbes National Security Commission of Emerging BiotechTopics Covered:bioconvergence, deep tech venture capital, synthetic biology investing, biomanufacturing, life science tools, clinical diagnostics, industrial biotech, bioeconomyHave a question or comment? Message us here:Text or Call (804) 505-5553Instagram / Twitter / LinkedIn / Youtube / <a href="https://www.messaginglab.com/groweverything" target="_blank" rel="ugc noopener n
- Oct 2, 202650 min
201. Out of Cell Experience: Michael Heltzen Drives Pure Chemistry at eXoZymes
Michael Heltzen, CEO of Exozymes, joins Grow Everything to explain how cell free biomanufacturing is opening new possibilities for natural products, nutraceuticals, and medicines. Michael shares why engineered enzymes can make high purity molecules without relying on living cells, how Exozymes moved its NCT program from discovery toward commercial manufacturing in less than two years, and why its capital light partnership model is central to scaling impact. The conversation also explores AI guided enzyme design, digital twins for manufacturing, rare cannabinoids, downstream processing, and the disciplined focus required to turn a broad biotechnology platform into real products.Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and speak with the leaders and innovators using biology to change the world. Biology is the world’s oldest technology, and it can be engineered. So, what are we growing?Learn more at www.messaginglab.com/groweverythingChapters: Michael Heltzen and the Exozymes mission Why cell free manufacturing can unlock inaccessible natural products Combining molecular biology, computation, and AI guided enzyme design From laboratory platform to industrial scale production Commercial partnerships and the NCT market opportunity Rare cannabinoids and a new toolkit for medicinal chemistry The capital light licensing model for biomanufacturing Downstream processing, purity, and investor skepticism The future of sustainable enzyme driven chemical manufacturing Key takeaways on focus, partnerships, and platform innovationLinks and Resources:eXoZymeseXoZymes Awarded $2 Million NIH Grant to Advance Cannabinoid Analogs for Drug DiscoveryeXoZymes’ Cell-Free Biomanufacturing Platform Gets Positive Feedback from Cayman ChemicalMichael Heltzen LinkedIneXoZymes on LinkedIn129. No Cells? No Problem! eXoZymes' Michael Heltzen on the Future of Microbe-Free Biotech176. Dare to Commercialize: Damien Perriman’s eXoZymes Playbook51. Cell-Free, Problem-Free: Enzyme Alchemy with Alex Rosay at Cascade Biocatalysts85. Always Be Brewing: Continuous Fermentation with Cauldron's Michele StansfieldTopics Covered:cell-free biomanufacturing, enzyme engineering, exozymes, biosynthesis, cannabinoids, NCT (N-trans-caffeoyltyramine), synthetic biology, AI-driven enzyme design, scalable bioproduction, sustainable chemicalsHave a question or comment? Message us here:Text or Call (804) 505-5553Instagram / Twitter / LinkedIn / Youtube / Grow EverythingMusic by: Nihilore Production by: Amplafy Media
- Sep 25, 20261h 28m
200. That's One Cell of a Machine: Jason Kelly of Gingko Automates Labs to Accelerate Discovery
For the 200th episode of Grow Everything, Karl Schmieder and Erum Azeez Khan talk with Jason Kelly, co-founder and CEO of Ginkgo Bioworks and former chair of the US National Security Commission on Emerging Biotechnology, about why biology is still so hard to engineer. Jason explains why a cell is the only coded substrate we have besides a computer, why the real bottleneck is tooling rather than ideas, and why Ginkgo moved from royalty based research partnerships to selling robotic hardware and lab data as a service. Using a subway, car and Waymo analogy, he separates automation from autonomy and makes the case for replacing the manual lab bench, which eats roughly 97 percent of research spending while running 40 hours out of 168. He walks through Ginkgo's Boston system of 105 robots running 24/7, new autonomous labs for MIT, Caltech, Northwestern and the University of Maryland, and the OpenAI project where GPT-5 ran 30,000 experiments a week and beat state of the art in cell free protein synthesis by 40 percent. He also lays out the policy stakes as drug discovery shifts to China, and why the day biology becomes predictably easier to engineer, biotech gets bigger than tech.Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and speak with the leaders and innovators using biology to change the world. Biology is the world’s oldest technology, and it can be engineered. So, what are we growing?Learn more at www.messaginglab.com/groweverythingChapters: A cell is a machine that can do a million other things AI data centers, contamination, and the waste to value opportunity Biosecurity, guardrails, and who is accountable for AI in biology Ginkgo's mission: programming a computer you did not design Why Ginkgo reset its business model from royalties to tools and data Subway, car, Waymo: what an autonomous lab actually means Inside Nebula: 105 robots, 24/7 lab work, and autonomous labs for MIT and Caltech The end of experimental scarcity and what scientists do next Offshoring biotech to China and the policy fix Jason wants Simulating cells, Moore's law for biology, and the markets beyond pharmaLinks and Resources:Gingko BioworksGingko Bioworks - Automation product Jason Kelly linkedinGinkgo Bioworks Joins ARPA-H GIVE Program to Build Autonomous Manufacturing System for Individualized RNA MedicinesNational Security Commission on Emerging BiotechSingapore is building supercomputer that runs on human brain cellsWater in Wyoming data center contaminated with cupriavidus gilardii112. The Baked-In Future of Science: Nick Edwards on Potato AI’s Quest to Become Your AI Scientist5. Dreaming in Biology: Tales from the Ginkgo Bioworks Studio50. The Dye-Hard Innovator: Natsai Chieza Designs Change for the Fashion Industry and the WorldTopics Covered:autonomous labs, laboratory robotics, AI in biotechnology, synthetic biology, bioengineering, biological automation, data as a service, biotech infrastructure, cell engineering, programmable biology<st
- Sep 18, 202649 min
199. Space, the Final Fermenter: Mario Maggio Brews Biology in Orbit with Ambrosia Space
Biology may be the most important technology we take off planet, and Mario Maggio is building the hardware to prove it. The founder and CEO of Ambrosia Space joins Erum Azeez Khan and Karl Schmieder to explain why space bioprocessing has been stuck at 10 to 20 milliliters while bench scientists on Earth work at 250 milliliters and beyond, and what changes when a two and a half liter fed batch bioreactor with pH, dissolved oxygen, and total cell density sensors finally flies. Mario traces his path from aerospace propulsion and the Nova C lunar lander at Intuitive Machines to life support systems at Paragon and Axiom Space, and the realization that biology is the best CO2 scrubber, oxygen source, and chemical factory available for long duration missions where petroleum, farms, and easy resupply do not exist. The conversation digs into the engineering reality of fluids and gas in microgravity, why glass and ceramics never fly, the stainless steel and aluminum builds that replace them, the intentional and unintentional bacteria that come with building a bioreactor from scratch, and the NASA TechLeap winning CellSep continuous flow centrifuge that carries cells and secreted products into downstream processing without gravity. Mario also lays out the near term commercial case, from protein crystallization and monoclonal antibodies that behave differently in orbit to biofuels, vitamin production, medicines, and the big silver tanks that will feed astronauts because there will be no farms or cattle. He offers a candid read on artificial gravity gradients, why the Moon matters for building large vehicles in space, and why the same hardware that grows yeast for beer on Mars becomes the root of better biomanufacturing on Earth. Erum and Karl open with field notes from Bio Innovations North America in Omaha, including Midwest feedstock advantage, consortia momentum, the 30 percent of cost hiding in downstream processing, and why Smucker and Mars are actively scouting biotech innovators.Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and speak with the leaders and innovators using biology to change the world. Biology is the world’s oldest technology, and it can be engineered. So, what are we growing?Learn more at www.messaginglab.com/groweverythingChapters: Why Biology Is the Best Commercial Case for Space Bio Innovations North America and the Midwest Bioeconomy Why Smucker and Mars Are Scouting Biotech Innovators Inside Ambrosia Space: Bioreactors Built for Orbit Scaling Past 150 Milliliters: Space Biology's Volume Problem Stainless Steel, Leaks, and Why Glass Never Flies NASA TechLeap and the CellSep Continuous Flow Centrifuge Protein Crystals and Monoclonal Antibodies Made in Microgravity Artificial Gravity, Lunar Bases, and Closing the Loop on Life Support Quick Fire: Space Food Reality, HAL, and Biologics in OrbitLinks and Resources:Mario MaggioAmbrosia Space LinkedInAmbrosia Space111. Space Genes and Subway Scenes: Chris Mason on Planning Life’s Next Big Leap93. Houston, We Have a Protocol: NASA's Kate Rubins on Biotech in Space187. One Small Step for a Microbe: Lynn Rothschild’s Leap from Astrobiology to Bioengineering at NASA185. Brick Happens: Chris Maurer of Redhouse Studio Redesigns Remote Living for Earth and Mars152. Crystals in the Cosmos: Varda Rewrites Drug Formulation in MicrogravityGrow E
- Sep 11, 20261h 2m
198. A Grain of Truth: Chef Pierre Thiam Scaled Fonio Without Losing Its Roots
Chef and entrepreneur Pierre Thiam joins Grow Everything to explain how fonio, a resilient ancient grain from West Africa, can become a platform for biodiversity, regenerative agriculture, food security, and farmer prosperity. Pierre traces his journey from studying physics and chemistry to discovering the kitchen as a larger system connecting culture, health, ecology, and economics. He shares why fonio is nutritionally dense, gluten free, drought resistant, fast cooking, and versatile, as well as how Yolélé is building aggregation centers and modern processing infrastructure while keeping cultivation knowledge and ownership with smallholder farming communities. The conversation explores how biotechnology can complement biodiversity, why flavor must lead climate friendly food adoption, how underutilized crops can create clean label ingredients and new commercial markets, and why food can serve as a powerful tool for diplomacy and cultural understanding. For founders, scientists, investors, and builders in the bioeconomy, Pierre offers a human centered model of innovation that begins with nature, respects generational knowledge, and uses technology to unlock solutions that have been in front of us all along.Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and speak with the leaders and innovators using biology to change the world. Biology is the world’s oldest technology, and it can be engineered. So, what are we growing?Learn more at www.messaginglab.com/groweverythingChapters: Why flavor must lead sustainable food adoption Artificial intelligence for science and protein design Pierre Thiam connects cooking, chemistry, culture, and diplomacy What fonio tastes like and why chefs love its versatility Scaling fonio through farmer centered supply chains and global markets Human centered design for West African farming communities Delicious first: the strategy behind climate friendly food adoption Biodiversity, forgotten crops, and the future of food security How biotechnology and local knowledge can work together Building healthier diets and stronger farming communitiesLinks and Resources:Chef Pierre ThiamTeranga - Senegalese RestaurantYolélé FoodsThe Fonio CookbookChief Pierre Thiam Instagram197. What’s in Your Cart? A Grocery Store Walkthrough of Next-Gen Food Innovation196. Beyond the Red Tape: Greg Jaffe on Policy as an Accelerator for Bio-InnovationNew Evidence points to ‘Ghost DNA’Claude opens 10,000 free seats to scientistsDavid Kong's class - How To Grow Almost AnythingBioInnovations Events - For 25% off use code: Grow EverythingGrow Everything LinkedInTopics Covered:Fonio, West African cuisine, sustainable food systems, regenerative agriculture, food biodiversity, underutilized crops, food diplomacy, Bambara groundnuts, climate-resilient crops, YoléléHave a question or comment? Message us here:Text or Call (804) 505-5553<a href="https://www.instagram.com/groweverythingpod/" target="_bla
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About Grow Everything Biotech Podcast
Grow Everything explores the world of biology as technology. Hosts Erum Khan and Karl Schmieder interview leaders and influencers biologizing industries with tools like synthetic biology, precision fermentation, bioprospecting, and more. These companies make biomaterials from waste, cosmetics that restore healthy hair and skin, and delicious cultivated foods in a bioreactor and so much more. Join us as we discuss the latest and greatest across biotech, engineered biology, entrepreneurship, and culture and how this transition is solving healthcare and climate change challenges.
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