Gen C

IOTA’s Karen O'Brien on The $35 Trillion Bet on Industrial Blockchain

January 27, 2026·32 min
Episode Description from the Publisher

IOTA CMO, Karen O’Brien reveals the high-stakes roadmap to transform the $35 trillion global trade industry from archaic paper systems into a frictionless, blockchain-powered infrastructure. Karen O’Brien, CMO of IOTA, breaks down why the industry is finally hitting a much-needed trust reset, trading short-term hype for the work of fixing global trade. O’Brien touches on how she’s helping solve the $35 trillion "paper and email" bottleneck to create an invisible backbone for global supply chains—a true blockchain for machines. - Links mentioned from the podcast:  Karen's Twitter  IOTA Website - Follow us on Twitter: Sam Ewen, CoinDesk - "Gen C" features host Sam Ewen. Executive produced by Uyen Truong.

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