Gen C

Building Autonomous Health Systems in the Age of AI with Bryan Johnson

January 13, 2026·29 min
Episode Description from the Publisher

From building Braintree to launching Blueprint, Bryan Johnson reveals how the systems architecture of FinTech and the philosophy of crypto are powering a new, autonomous roadmap to reverse human aging and operationalize immortality. Founder and CEO of Blueprint and Don’t Die, Bryan Johnson, joins Gen C to discuss why the philosophy of crypto has the same mindset required to solve human aging. Bryan reveals how he is applying FinTech systems-thinking to the human body through "Autonomous Health" and bio-algorithms. We explore his journey to reverse his biological age and why the tech community is the primary driver of the next great evolution in human existence. - Links mentioned from the podcast:  Bryan's Twitter  Blueprint Website Don’t Die Website - Follow us on Twitter:  Sam Ewen, CoinDesk - From our sponsor: Check out CoinDesk's research report on KuCoin at: https://www.coindesk.com/research/kucoin-hits-record-market-share-as-2025-volumes-outpace-crypto-market - "Gen C" features host Sam Ewen. Executive produced by Uyen Truong.

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