Free Daily Podcast Summary
Freely Filtered, a NephJC Podcast: Daily Summaries Delivered
by NephJC Team
Twice monthly (aspirational) recap of the NephJC journal club. NephJC reviews the most important manuscripts which are driving nephrology forward and improving our understanding of the kidney.
Latest Episodes
The most recent episodes — sign up to get AI-powered summaries of each one.
- 2 weeks ago1h 32m
FF99 Late Breaking and High Impact Clinical Trials Session at KidneyWk: Pregnancy Outcomes after Kidney Donation
This is our second time releasing a podcast simultaneous with presentation and publication. Super exciting.This podcast covers a retrospective trial study on pregnancy complications in kidney donors. The FiltrateJoel Topf @kidney_boySwapnil Hiremath @hswapnil.medsky.socialAnna Gaddy @GaddyAnnaRNayan Arora @captainchlorideSophia Ambruso @sophia_kidneySpecial GuestsAmit Garg @AmitXGarg, Nephrologist at Western University, London and PI of the current studyEditingJoel TopfThe Kidney Connection written and performed by Timothy YauShow NotesPrevious appearances by Dr Garg:Episode 56 MyTEMPEpisode 63 Enhance Access to Kidney Transplantation and Living Kidney Donation (EnAKT LKD) (Late breaking and High impact clinical trial session at KidneyWeek 2023 in PhiladelphiaOur last attempt to podcast about preeclampsia did not go so well: Episode 70: Predicting Preeclampsia, the PRAECIS trial and Episode 70b Do Over: Predicting Preeclampsia, the PRAECIS trial (https://www.nephjc.com/freelyfiltered/2024/freely-filtered-70b-do-over-preeclampsia) The use of the words “men” and “women” in scientific papers, an editorialThe Big Ask, The Big GiftGarg’s prior work on male donors and scrotal surgery: Risk for Scrotal Surgery After Laparoscopic Donor Nephrectomy : A Population-Based Cohort Study PubMedGarg’s prior work on donor and pregnancy outcomes: Gestational Hypertension and Preeclampsia in Living Kidney Donors NEJM The Consensus Statement of the Amsterdam Forum on the Care of the Live Kidney Donor 2004 TransplantationKDIGO 2017 Clinical Practice Guideline on the Evaluation and Care of Living Kidney Donors <a target="_blank" href="https://
- 3 weeks ago1h 28m
FF98 FIND-CKD Finerenone Tackles non-diabetic CKD
The FiltrateJoel Topf @kidney_boySwapnil Hiremath @hswapnil.medsky.socialAnna Gaddy @annagaddy.bsky.social Natalie Freidin Program director at Medical University of South CarolinaSpecial GuestsBrendon “Brendo” Neuen The first Five-Time guest on Freely Filtered. Nephrologist and Director, Kidney Trials, Royal North Shore Hospital. Associate Professor of Medicine at the George InstituteEditingNatalie FreidinThe Kidney Connection written and performed by Timothy YauShow NotesDonate to the fall pledge drive: https://www.nephjc.com/news/2026/9/8/nephjc-fall-pledge-drive Come to the ASN NephJC Night in Denver the Kidney Week: https://www.nephjc.com/news/2026/9/13/the-2026-nephjc-night FIND-CKD: Finerenone in Persons with Chronic Kidney Disease without Diabetes NEJM | NephJC2-year GFR data on sibeprelimab Incidence of ESRD in the US due to IgAN (estimate using USRDS data) Heinz 57 wikipediaRandomised placebo-controlled trial of effect of ramipril on decline in glomerular filtration rate and risk of terminal renal failure in proteinuric, non-diabetic nephropathy. The Lancet 1997. The REIN trial for people with nephrotic range proteinuria (>3 grams/day)Renoprotective properties of ACE-inhibition in non-diabetic nephropathies with non-nephrotic proteinuria, The Lancet 1999 REIN Stratum 1 for sub-nephrotic range proteinuria (1-3 grams/day)Effect of Finerenone on Chronic Kidney Disease Outcomes in Type 2 Diabetes FIDELIO in NephJC | NEJMBenefits of aldosterone receptor antagonism in chronic kidney disease BARACK-D RCT PubMedWe discussed the run in. Importantly the run in for FIDELIO and FIGRO did not giv
- Sep 27, 20261h 20m
FF97 MERCURI-2, Can a Flozin prevent AKI?
Bypass surgery continues to be the laboratory where we test the most innovative ideas on the prevention of AKIThe FiltrateJoel Topf @kidney_boySwapnil Hiremath @hswapnil.medsky.socialVipin VargheseSophia AmbrusoSpecial GuestsRahul Ganatra Deputy Editor NEJM Clinician. https://clinician.nejm.org/editors/AU3406Jay Koyner Professor of Medicine, University of Chicago. https://www.uchicagomedicine.org/find-a-physician/physician/jay-koynerEditingVipin VargheseThe Kidney Connection written and performed by Timothy YauShow NotesBack to the Future: https://youtu.be/BDuZqYeNiOA?is=r-RE2DgIDBazRAlWAmino Acids for AKI: The PROTECTION Study NephJC: Trial by Combat: Do Amino Acids provide PROTECTION to the Kidneys?In 2016 the FDA posted a warning that SGLT2i could induce AKI. This Nature Reviews Nephrology explores possible mechanisms for the AKI: Acute kidney injury from SGLT2 inhibitors: potential mechanisms https://www.nature.com/articles/nrneph.2016.159But by 2019 the SMART-C Collaboration was looking at the risk of AKI in the large RCTs and found Flozins to be protective: SGLT2 inhibitors for the prevention of kidney failure in patients with type 2 diabetes: a systematic review and meta-analysis. https://www.thelancet.com/journals/landia/article/PIIS2213-8587(19)30256-6/abstractIf you are actually looking for the best data you should look at the updated meta-analysis from 2025 which extends the findings to patients with and without diabetes and to patients with and without CKD: SGLT2 Inhibitors and Kidney Outcomes by Glomerular Filtration Rate and Albuminuria https://pmc.ncbi.nlm.nih.gov/articles/PMC12595549/ 2012 KDIGO AKI Guidelines: https://kdigo.org/wp-content/uploads/2016/10/KDIGO-2012-AKI-Guideline-English.pdfThe 2025/2026 AKI Draft guidelines: https://kdigo.org/wp-content/uploads/2026/03/KDIGO-2026-AKI-AKD-Guideline-Public-Review-Draft-March-2026.pdfMeta-analysis of frusemide to prevent or treat acute renal failure https://www.bmj.com/content/early/2005/12/31/bmj.38902.605347.7C<p class="" data-rte-preserve-empty="true
- Aug 30, 20261h 20m
FF96 MAJESTY, or Mentor Two
The FiltrateJoel Topf @kidney_boySwapnil Hiremath @hswapnil.medsky.social Natalie Freidin Program director at Medical University of South CarolinaAC @medpeedskidneys.bsky.socialSpecial GuestsFernando Fervenza Professor of Medicine, The Mayo ClinicEditingVip VerguesThe Kidney Connection written and performed by Timothy YauShow Notes MENTOR NephJC | NEJM | Freely Filtered episode 7PLA2r in 2009 M-Type Phospholipase A2 Receptor as Target Antigen in Idiopathic Membranous Nephropathy NEJM MAJESTY NephJC | NEJM Obinutuzumab or Tacrolimus in Primary Membranous NephropathyGiuseppe Remuzzi discovers rituximab works in primary membranous. Rituximab for idiopathic membranous nephropathy The Lancet 2002Fervenza’s 15-person study of Rituximab treatment of idiopathic membranous nephropathy Kidney International 2008.Larry Beck’s NEJM PLA2r study M-Type Phospholipase A2 Receptor as Target Antigen in Idiopathic Membranous Nephropathy NEJM 20092011 (not 2010) JASN paper where using banked serum from two prior rituximab studies in membranous nephropathy, Beck and Fervenza showed that declines in anti-PLA2R antibodies preceded reductions in proteinuria and predicted subsequent clinical remission, establishing the concept that immunologic remission precedes clinical remission. Rituximab-Induced Depletion of Anti-PLA2R Autoantibodies Predicts Response in Membranous Nephropathy PubMed The National Institute of Animal Health…a Fervenza fictionRobert A. Star, M.D. NIHDaniel C. Cattran, M.D. NephCure<p data-rte-preserve-empty="true" style="white-space:p
- Aug 23, 20261h 6m
FF95 The PUSH trial. Push it real good!
The FiltrateJoel Topf@kidney_boyVipin Verghese@vipvargh.bsky.socialNayan Arora @captainchlorideSpecial GuestsDavid Goldfarb Professor of Medicine, NYU (COI)Megan Prochaska Assistant professor of medicine at University of ChicagoJohn Asplin Medical Director Consultant LithoLink (Twitter)EditingAnna GaddyThe Kidney Connection written and performed by Timothy YauShow Notes Kidney Treks, University of Chicago. For medical students.The Push Trial: Prevention of urinary stones with hydration: a randomised clinical trial of an adherence intervention NephJC Short | The LancetCharlie Pak trial showing increased urine volume reduced risk of kidney stones. Evidence justifying a high fluid intake in treatment of nephrolithiasis PubMedThe Borghi Trial: Urinary volume, water and recurrences in idiopathic calcium nephrolithiasis: a 5-year randomized prospective study PubMedMedical Management of Kidney Stones: AUA Guideline (2026)Weird little trial Asplin mentioned with amlodipine. But it was actually verapami. By Kemal Sarical: The effect of calcium channel blockers on stone regrowth and recurrence after shock wave lithotripsy PubMedBorghi’s other giant study in kidney stones: Comparison of Two Diets for the Prevention of Recurrent Stones in Idiopathic Hypercalciuria NEJMThe No Stone Trial: Hydrochlorothiazide and Prevention of Kidney-Stone Recurrence NephJC | NEJMGary Curhan epidemiologic data from the Nurses Health Study and the Health Professionals Follow-up Study: Twenty-four-hour urine chemistries and the risk of kidney stones among women and men PubMedGary Curhan epidemiologic data on sugar sweetened beverages and risk of kidney stones. Soda and other beverages and the risk of kidney stones PubMedEric Topol’s <a target="_
- Jul 17, 20261h 14m
FF94 C3 Glomerulopathy with Carla Nester
The FiltrateJoel Topf kidneyboy.bsky.socialSwapnil Hiremath @hswapnil.medsky.social Natalie Freidin Program director at Medical University of South CarolinaSophia Ambruso @sophia_kidneyAC @medpeedskidneys.bsky.socialSpecial GuestsCarla Nester, Professor of Medicine, Professor of Pediatrics, University of Iowa. Senior author of ValiantEditingNatalie FreidinThe Kidney Connection written and performed by Timothy YauShow Notes Trial of Pegcetacoplan in C3 Glomerulopathy and Immune-Complex MPGN NEJM | NephJCTubular SecretionsSwapnil: City of Last Chances by Adrian Tchaikovsky (Amazon)Natalie: Heated Rivalry, the books by Rachel ReidCarla: Rowing and gold fiber embroideryAC: Audiobooks, that are appropriate for children: The Giver and Tuck EverlastingSophia: Greeking Out podcast and the Wheel of Time by Robert Jordan (Wikipedia)Joel: This is How You Lose The War by Amal El-Mohtar and Max Gladstone (Amazon)
- Jun 30, 20261h 30m
FF93 Hyponatremia Interventional Trial
The FiltrateJoel Topf kidneyboy.bsky.socialSwapnil Hiremath @hswapnil.medsky.social Pedro Teixeira @nephcrit.bsky.socialSpecial GuestsEwout J. Hoorn, Professor of Medicine Erasmus MC, Netherlands. One of the primary authors.Harish Seethapathy, Assistant physician at Massachusetts General HospitalEditingVipin VergheseThe Kidney Connection written and performed by Timothy YauShow Notes A Randomized Trial of Targeted Hyponatremia Correction in Hospitalized Patients in NEJM Evidence, in PubMed, in NephJCSeethapathy: Severe Hyponatremia Correction, Mortality, and Central Pontine Myelinolysis in NEJM EvidenceMacMillan: Osmotic Demyelination Syndrome in Patients Hospitalized with Hyponatremia in NEJM EvidenceSALSA: Risk of Overcorrection in Rapid Intermittent Bolus vs Slow Continuous Infusion Therapies of Hypertonic Saline for Patients With Symptomatic Hyponatremia: The SALSA Randomized Clinical Trial in JAMA Internal MedicineSALT 1 and 2: Tolvaptan, a Selective Oral Vasopressin V2-Receptor Antagonist, for Hyponatremia in NEJM Hyponatremia registry: Current treatment practice and outcomes. Report of the hyponatremia registry in Kidney InternationalThe Richard Sterns’ article on the lower mortality with more severe hyponatremia: Mortality and Serum Sodium: Do Patients Die from or with Hyponatremia? in CJASNThe European Hyponatremia Guidelines: Clinical practice guideline on diagnosis and treatment of hyponatraemia in The European Journal of EndocrinologyThe American Hyponatremia Guidelines: Diagnosis, Evaluation, and Treatment of Hyponatremia: Expert Panel Recommendations in American Journal of MedicineTreating hyponatremia: damned if we do and damned if we don't by Tom Berl in <a target="_blank" href="https://www.kidney-international.o
- Jun 9, 20261h 35m
FF92 Live from Dublin, The Irish Nephrology Society
The FiltrateJoel Topf kidneyboy.bsky.socialSpecial GuestsDr. Samir Parikh, President of the American Society of NephrologyProf. Donal Reddan, President, Irish Nephrology SocietyProf. Catherine GodsonEditing Joel TopfThe Kidney Connection written and performed by Timothy YauShow Notes Tubular SecretionsJoel Topf, the Dublin Port Greenway LinkCatherine Godson: never heard of the Dublin Port GreenwaySamir Parikh: Trinity College Dublin and specifically the Eavan Boland Library, named after the Irish poet. Donal Reddan: Something about rugby
Get Freely Filtered, a NephJC Podcast summaries in your inbox
Free AI-powered daily recaps. Key takeaways, quotes, and mentions — in a 5-minute read.
Get Free Summaries →Free forever for up to 3 podcasts. No credit card required.
You Might Also Like
Listeners also like.
ICU Ed and Todd-Cast
Eddie and Todd
Frankly Speaking About Family Medicine
Discusses current topics and developments in primary care and family medicine.
Red Pill Your Healthcast
Two healthcare providers discuss overlooked health issues and empower listeners to make informed decisions for their families.
The Internet Book of Critical Care Podcast
A podcast exploring critical care medicine through chapter discussions and evidence-based updates from The Internet Book of Critical Care.
In the Interim...
Explores Bayesian statistics and adaptive clinical trial designs in medical research with insights from industry experts.
The House of Pod
A gastrointestinal doctor and colleagues discuss medicine with humor and insight.
The Curbsiders Internal Medicine Podcast
Expert-led internal medicine discussions with clinical insights and humor for primary care and hospital medicine providers.
Vet Rounds
Dr Sandy Karl CertAVP ECC
Get Better Faster
Doctors and researchers discuss functional medicine and root-cause approaches to chronic illness and health optimization.
The VPZD Show
Two physicians discuss healthcare, medicine, and policy from a contrarian, middle-ground perspective.
This Week in Cardiology
A weekly summary and analysis of key developments in cardiology for healthcare professionals.
Unbiased Science
Dr. Jess Steier and guests analyze viral health claims using scientific evidence and explain key findings for everyday conversations.
About Freely Filtered, a NephJC Podcast
Twice monthly (aspirational) recap of the NephJC journal club. NephJC reviews the most important manuscripts which are driving nephrology forward and improving our understanding of the kidney.
Customized Recaps
AI-powered recaps with compact key takeaways, quotes, and insights.
Straight to Your Inbox
Get key takeaways from Freely Filtered, a NephJC Podcast in a 5-minute read.
Save Hours Every Week
Stay current on your favorite podcasts without falling behind.
Frequently Asked Questions
What is Podzilla's Freely Filtered, a NephJC Podcast daily summary?
It's a free AI-powered email that summarizes new episodes of Freely Filtered, a NephJC Podcast as soon as they're published. You get the key takeaways, notable quotes, and links & mentions — all in a quick read.
How does the Freely Filtered, a NephJC Podcast podcast summary work?
When a new episode drops, our AI transcribes and analyzes it, then generates a personalized summary tailored to your interests and profession. It's delivered to your inbox every morning.
Is this an official Freely Filtered, a NephJC Podcast product?
No. Podzilla is an independent service that summarizes publicly available podcast content. We're not affiliated with or endorsed by NephJC Team.
Can I get summaries of other podcasts too?
Absolutely! The free plan covers up to 3 podcasts, any in the catalog. Basic raises that to 15, Pro to 40 and Max to 100. Browse our full catalog at /podcasts.
What topics does Freely Filtered, a NephJC Podcast cover?
Freely Filtered, a NephJC Podcast covers topics including Science, Medicine, Fitness, Health & Fitness. Our AI identifies the specific themes in each episode and highlights what matters most to you.
Start getting Freely Filtered, a NephJC Podcast summaries tomorrow morning.
Free forever for up to 3 podcasts. No credit card required.
Free forever for up to 3 podcasts. No credit card required.