Episode 79: Mechanical engineer Mason Chilmonczyk on fixing mass spec's bubbles, clogs, and leaks

Mechanical engineer Mason Chilmonczyk, PhD (Andson Biotech) joins host David Oliva to explain why sample prep — not the mass spec itself — is the biggest bottleneck in LC-MS and native MS workflows. Mason breaks down the DynaChip, a microfluidic device that shrinks hours of buffer exchange into seconds, and shares how "democratizing" mass spec is opening the door for cell therapy manufacturers to catch analytical blind spots that traditional workflows miss. A must-listen for anyone working in native mass spec, biopharma analytics, or cell therapy development.