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Compound Interest from Semafor Business

Mark Cuban on his pharma fight, Dallas Mavs regrets, and the PE-ification of sports

April 28, 2026·52 min
Episode Description from the Publisher

Mark Cuban is on a mission to rid the US health care system of the middlemen he blames for soaring costs. Liz and Rohan dive into his approach with Cost Plus Drugs, which aims to disrupt the little-known middlemen driving up prescription drug prices. He also discussed soaring valuations in sports, his own regrets around the Dallas Mavericks sale, and offers a surprising assessment of TrumpRX. This season of Compound Interest is in partnership with Amazon Business. Amazon Business is a trusted partner that transforms business buying by combining Amazon's vast selection, competitive pricing, and fast delivery with added tools and insights to help businesses simplify purchasing, manage spend, and buy smarter. Photo Credit: Mark J. Rebilas-Imagn Images

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