Bringing Data and AI to Life

The Playbook To Building AI-Driven Innovation at Scale with Karen Pfeifer of Pythian

August 6, 2026·18 min
Episode Description from the Publisher

AI this, AI that - but how many of us are actually extracting its complete value and making it work for us? In this episode of Bringing Data and AI to Life, host and GVP Solutions Sales and Business Development at Informatica, Amy Horowitz sits down with Karen Pfeifer, Chief AI Officer at Pythian, to unravel the complexities of enterprise data and AI transformation. Drawing from her extensive experience at industry giants like Disney, Hulu, and Comcast, Karen shares invaluable insights on measuring data success through business impact, developing cross-functional teams, and navigating the challenges of AI governance. Her experiential perspectives offer practical wisdom on building trusted data foundations and embracing emerging trends like Agentic AI. Tune in for a reminder that the bridge between technical innovation and tangible business outcomes exists, and you can cross it!

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