ATTD: Advanced Technologies and Treatments for Diabetes

Fixed-Ratio Combinations (FRCs) in Practice

May 19, 2026·14 min
Episode Description from the Publisher

In this episode, host Bob Gabbay and his guest, Dr George Grunberger, Chairman of the Grunberger Diabetes Institute, discuss best practice and guidance around basal insulin and GLP-1 combinations.They discuss:What exactly fixed-ratio combinations are and the problems they tackleIdentifying patient candidates and timelines for starting FRCsMeaningful benefits of FRCs compared with basal insulin aloneConcerns and limitations of FRCsHow guideline recommendations currently position FRCs in diabetes managementDr George Grunberger, Chairman of the Grunberger Diabetes Institute in Michigan. George is also Clinical Professor of Internal Medicine at Wayne State University School of Medicine, and Professor of Internal Medicine at Oakland University William Beaumont School of Medicine.Explore more on the ATTD Education Portal. Register now to access exclusive content and stay ahead in the field!Make sure you’re subscribed to the ATTD Podcast feed today. Leave us a review and share with a colleague.

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