Dysfunction Mitochondria in Myositis-Driven Inflammation

As part of our special coverage of ACR Convergence 2026, we're joined by Christian Lood from the University of Washington to explore a surprising role mitochondrion may play in myositis. Long known as the powerhouse of the cell, mitochondria may do more than simply respond to inflammation. When damaged, they can release contents that trigger the immune system and potentially fuel inflammation. We discuss how mitochondria escape from injured muscle, their potential as markers of disease activity, and whether understanding these processes could lead to new treatments for juvenile dermatomyositis (JDM). Christian will present his talk, "Dysfunctional Mitochondria in Myositis-Driven Inflammation," on Sunday, November 8, at ACR Convergence 2026