Why 49ers' biggest test yet awaits at Lumen Field; plus, NFL business insights with Andrew Brandt

San Francisco hasn't forgotten how last season ended in an NFC Divisional Playoff loss to the Seahawks at Lumen Field. On this episode of "49ers Talk," co-hosts Matt Maiocco and Jennifer Lee Chan preview the 49ers' first crack at redemption against their NFC West rival in Week 5, and who will be available for the game as second-year defensive end Mykel Williams looks ready to make his season debut. Later, Matt talks with former NFL executive and agent Andrew Brandt about the business side of sports as they delve into the nitty-gritty of balancing professional contracts and salary caps.--(0:00) NFC West matchup brings extra juice in Week 5(5:00) 49ers playing numbers game with roster decisions(8:00) When is Bosa coming back?(10:00) Mykel Williams itching to return(19:00) Purdy having an elite start to season(40:00) Brandt breaks down how 49ers deal with Bosa’s massive contract next season Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.